Figure 6. This diagram shows the difficulty
that identical MC twins encounter when the blastocyst (a ball like stage
of embryonic development, see 6-A, TC) enters the mother’s womb and
imbeds in the nutrient lining (DB). At this stage, each twin is represented
by a few cells (the two inner cell masses - ICM). In a single pregnancy
(not pictured) the placenta will most likely develop normally (large, with
an umbilical cord in the middle of the placenta) if the pole containing
the inner cell mass enters the uterine lining first. Any rotation of the
blastocyst pole containing the inner cell mass will lead to a smaller defective
placenta. Since the cells that develop into the MC twins sit at opposite
ends (poles) of the blastocyst, as one twin’s cells imbed perfectly
(6 - B), the other twin’s cells move farther away from the lining
that provides nutrients from the mother. All MC twin blastocyst implantations,
therefore, represent a compromise and are prone to develop placentas that
are smaller and unequally shared by the twins. EE = endometrial gland; UV
= uterine blood vessel (Diagram courtesy of Dr. Emanual P. Gaziano)
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