
Am J Obstet Gynecol 1998 Nov;179(5):1155-61
Luke B, Min SJ, Gillespie B,
Avni M, Witter FR, Newman RB, Mauldin JG,
Salman FA, O'Sullivan MJ
Department of Obstetrics and Gynecology, University of Michigan
Medical
School, University of Michigan, Ann Arbor, MI, USA.
OBJECTIVE: It was our objective to evaluate the
association between early maternal weight gain (before 20 weeks),midpregnancy
weight gain (20-28 weeks), and late pregnancy weight gain (28
weeks to birth) with fetal growth and birth weight in twins .
STUDY DESIGN:
This historic cohort study was based on 1564 births of live twins
>/=28weeks'
gestation from Baltimore, Maryland, Miami, Florida, Charleston,
South Carolina, and Ann Arbor, Michigan.
RESULTS: Early fetal growth was
affected only by smoking and chorionicity. Factors in models of
both mid and late fetal growth included maternal age, pregravid
weight, parity, rates of early pregnancy and midpregnancy maternal
weight gain, smoking, and pre-eclampsia. Increasedmidpregnancy
fetal growth was associated
with early maternal weight gain (10.91 g/wk per pound perweek)
and midpregnancy maternal weight gain (15.89 g/wk per poundper
week). Increased late fetal growth was associated withearly maternal
weight gain (16.86 g/wk per pound per week)and midpregnancy maternal
weight gain (23.88 g/wk perpound per week). Increased birth weight
was associated withearly (283.02 g per pound per week), mid (163.58
g per pound per week), and late (69.76 g per pound per week)maternal
weight
gains.
CONCLUSIONS:
These findings confirm the importance of early maternal weight
gain in twin fetal growth and birth weight.
PMID: 9822493